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Monday, February 05, 2007

That's Funny...

Accidental discovery:

She was testing a compound called a PPAR-gamma modulator. It would never normally have been thought of as a cancer drug, or in fact a drug of any kind.

"I made a calculation error and used a lot more than I should have. And my cells died," Schaefer said.

A colleague overheard her complaining. "The co-author on my paper said,' Did I hear you say you killed some cancer?' I said 'Oh', and took a closer look."

They ran several tests and found the compound killed "pretty much every epithelial tumor cell lines we have seen," Schaefer said. Epithelial cells line organs such as the colon, and also make up skin.

"The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' (I found it!) but 'That's funny ...'" - Isaac Asimov

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